Articles By Year

2021

Accelerator-based BNCT for patients with recurrent glioblastoma: a multicenter phase II study

Authors:   Shinji Kawabata,Minoru Suzuki,Katsumi Hirose,Hiroki Tanaka,Takahiro Kato,Hiromi Goto,Yoshitaka Narita,Shin-Ichi Miyatake, Journal: Neuro-Oncology…

ACT-3 Reactor-based boron neutron capture therapy with add-on bevacizumab for recurrent malignant glioma: The final report

Authors:   Motomasa Furuse,Shinji Kawabata,Masahiko Wanibuchi,Hiroyuki Shiba,Koji Takeuchi,Natsuko Kondo,Hiroki Tanaka,Yoshinori Sakurai,Minoru Suzuki,Koji Ono,Shin-Ichi…

Boron Neutron Capture Therapy Study of 10B Enriched Nanostructured Boron Carbide Against Cervical Cancer and Glioblastoma Cell Line

Authors:   Manjot Kaur,Paviter Singh,Ramovatar Meena,Fumiko Nakagawa,Minoru Suzuki,Hiroyuki Nakamura,Akshay Kumar, Journal: Journal of…

2020

A 50 kW Liquid-Lithium Target for BNCT and Material-Science Applications

Authors:   Michael Paul, Ido Silverman, Shlomi Halfon, Semion Sukoriansky, Boris Mikhailovich, Tala…

A simple approximation for the evaluation of the photon iso-effective dose in Boron Neutron Capture Therapy based on dose-independent weighting factors

Authors:   María Pedrosa-Rivera,Javier Praena,Ignacio Porras,María Ruiz-Magaña,Carmen Ruiz-Ruiz, Journal: Applied Radiation and Isotopes…

2019

4-Borono-2- 18 F-fluoro-l-phenylalanine PET for boron neutron capture therapy-oriented diagnosis: overview of a quarter century of research

Authors:   Kiichi Ishiwata Journal: https://doi.org/10.1007/s12149-019-01347-8 Abstract: 4- 10 B-Borono-2- 18 F-fluoro-l-phenylalanine (…

Bevacizumab treatment for radiation brain necrosis: Mechanism, efficacy and issues

Authors:   Hongqing Zhuang,Siyu Shi,Zhiyong Yuan,Joe Chang Journal: Molecular Cancer https://doi.org/10.1186/s12943-019-0950-1 Abstract: Vascular…

BNCT induced immunomodulatory effects contribute to mammary tumor inhibition

Authors:   Aslam Khan,Charlie Maitz,Cai Quanyu,Fred Hawthorne Journal: PLoS ONE https://doi.org/10.1371/journal.pone.0222022 Abstract: In…

Boron delivery for boron neutron capture therapy targeting a cancer-upregulated oligopeptide transporter

Authors:   Junji Miyabe,Ryuichi Ohgaki,Keijiro Saito,Ling Wei,Lili Quan,Chunhuan Jin,Xingming Liu,Suguru Okuda,Shushi Nagamori,Hiroshi Ohki,Kazuo…

Charged particle spectrometry to measure 10 B concentration in bone

Authors:   L. Provenzano,S. Bortolussi,S.J. González,I. Postuma,N. Protti,A. Portu,M.S. Olivera,L.M. Rodriguez,D. Fregenal,S. Altieri,…

2018

A realistic appraisal of boron neutron capture therapy as a cancer treatment modality

Authors:   Rolf F Barth, Zizhu Zhang, Tong Liu Journal: Cancer Commun. https://doi.org/10.1186/s40880-018-0280-5…

Beam shaping assembly study for BNCT facility based on a 2.5 MeV proton accelerator on Li target

Authors:   Fantidis J.G. Journal: Journal of Theoretical and Applied Physics https://doi.org/10.1007/s40094-018-0312-1 Abstract:…

Boron delivery agents for neutron capture therapy of cancer

Authors:   Rolf F Barth, Peng Mi, Weilian Yang Journal: Cancer Commun. https://doi.org/10.1186/s40880-018-0299-7…

2017

Abscopal effect of boron neutron capture therapy (BNCT): proof of principle in an experimental model of colon cancer

Authors:   Verónica Trivillin,Emiliano Pozzi,Lucas Colombo,Silvia Thorp,Marcela Garabalino,Andrea Hughes,Sara González,Rubén Farías,Paula Curotto,Gustavo Cruz,Daniel…

An accelerator-based Boron Neutron Capture Therapy (BNCT) facility based on the 7Li(p,n)7Be

Authors:   Musacchio González E., Martín Hernández G. Journal: Nuclear Instruments and Methods…

Boron neutron capture therapy (BNCT) translational studies in the hamster cheek pouch model of oral cancer at the new “B2” configuration of the RA-6 nuclear reactor

Authors:   Andrea Hughes,Juan Longhino,Esteban Boggio,Vanina Medina,Diego Lamas,Marcela Garabalino,Elisa Heber,Emiliano Pozzi,María Itoiz,Romina Aromando,David…

2016

Boron neutron capture synovectomy (BNCS) as a potential therapy for rheumatoid arthritis: radiobiological studies at RA-1 Nuclear Reactor in a model of antigen-induced arthritis in rabbits

Authors:   Verónica Trivillin,Leandro Bruno,David Gatti,Mariela Stur,Marcela Garabalino,Andrea Hughes,Jorge Castillo,Emiliano Pozzi,Luis Wentzeis,Hugo Scolari,Amanda…

Boron Neutron Capture Therapy – A Literature Review

Authors:   Kavitaa Nedunchezhian, Nalini Aswath, Manigandan Thiruppathy, Sarumathi Thirugnanamurthy Journal: Journal of…

DNA damage induced by boron neutron capture therapy is partially repaired by DNA ligase IV

Authors:   Natsuko Kondo,Yoshinori Sakurai,Yuki Hirota,Hiroki Tanaka,Tsubasa Watanabe,Yosuke Nakagawa,Masaru Narabayashi,Yuko Kinashi,Shin Miyatake,Masatoshi Hasegawa,Minoru…

2015

A feasibility design study on a neutron spectrometer for BNCT with liquid moderator

Authors:   S. Tamaki,F. Sato,I. Murata, Journal: Applied Radiation and Isotopes https://doi.org/10.1016/j.apradiso.2015.08.010 Abstract:…

A new concept of a vacuum insulation tandem accelerator

Authors:   Sorokin I., Taskaev S. Journal: Applied Radiation and Isotopes https://doi.org/10.1016/j.apradiso.2015.06.015 Abstract:…

A study of gamma-ray and neutron radiation in the interaction of a 2MeV proton beam with various materials

Authors:   D. Kasatov,A. Makarov,I. Shchudlo,S. Taskaev, Journal: Applied Radiation and Isotopes https://doi.org/10.1016/j.apradiso.2015.08.011…

A study on the optimum fast neutron flux for Boron Neutron Capture Therapy of deep-seated tumors

Authors:   Rasouli F.S., Masoudi S.F. Journal: Applied Radiation and Isotopes https://doi.org/10.1016/j.apradiso.2014.11.016 Abstract:…

A theranostic approach based on the use of a dual boron/Gd agent to improve the efficacy of Boron Neutron Capture Therapy in the lung cancer treatment

Authors:   Diego Alberti,Nicoletta Protti,Antonio Toppino,Annamaria Deagostino,Stefania Lanzardo,Silva Bortolussi,Saverio Altieri,Claudia Voena,Roberto Chiarle,Simonetta Geninatti…

2014

10B-NMR determination of 10B-BPA, 10B-BPA–fructose complex and total 10B in blood for BNCT

Authors:   K. Yoshino,T. Yabe,T. Hattori,K. Saito,A. Ishikawa,H. Ohki, Journal: Applied Radiation and…

33S as a cooperative capturer for BNCT

Authors:   J. Praena,M. Sabaté-Gilarte,I. Porras,P.L. Esquinas,J.M. Quesada,P. Mastinu, Journal: Applied Radiation and…

33S for Neutron Capture Therapy: Nuclear Data for Monte Carlo Calculations

Authors:   I. Porras,M. Sabaté-Gilarte,J. Praena,J.M. Quesada,P.L. Esquinas, Journal: Nuclear Data Sheets https://doi.org/10.1016/j.nds.2014.07.058…

9Be(d,n)10B-based neutron sources for BNCT

Authors:   M.E. Capoulat,M.S. Herrera,D.M. Minsky,S.J. González,A.J. Kreiner, Journal: Applied Radiation and Isotopes…

A prospective study to assess the performance of the improved Boron Neutron Capture Therapy Facility in Argentina

Authors:   Lucas Provenzano,Rubén Farías,Juan Longhino,Esteban Boggio,María Herrera,Natanael Moijsecsiuck,Carlos Fernández,Gustavo {Santa Cruz},Sara González,…

A TPD and AR based comparison of accelerator neutron irradiation fields between 7Li and W targets for BNCT

Authors:   Kenichi Tanaka,Satoru Endo,Shunsuke Yonai,Mamoru Baba,Masaharu Hoshi, Journal: Applied Radiation and Isotopes…

2013

Apoptosis through Bcl-2/Bax and Cleaved Caspase Up-Regulation in Melanoma Treated by Boron Neutron Capture Therapy

Authors:   Fernanda Faião-Flores,Paulo Coelho,João Toledo Arruda-Neto,Silvya Maria-Engler,Manoela Tiago,Vera Capelozzi,Ricardo Giorgi,Durvanei Maria Journal:…

Biodistribution of sodium borocaptate (BSH) for boron neutron capture therapy (BNCT) in an oral cancer model

Authors:   Marcela Garabalino,Elisa Heber,Andrea Hughes,Sara González,Ana Molinari,Emiliano Pozzi,Susana Nievas,Maria Itoiz,Romina Aromando,David Nigg,William…

Boron neutron capture therapy (BNCT) for liver metastasis in an experimental model: Dose-response at five-week follow-up based on retrospective dose assessment in individual rats

Authors:   Emiliano Pozzi,Verónica Trivillin,Lucas Colombo,Andrea Hughes,Silvia Thorp,Jorge Cardoso,Marcela Garabalino,Ana Molinari,Elisa Heber,Paula Curotto,Marcelo…

2012

Boron neutron capture therapy (BNCT) for liver metastasis: Therapeutic efficacy in an experimental model

Authors:   Emiliano Pozzi,Jorge Cardoso,Lucas Colombo,Silvia Thorp,Andrea Hughes,Ana Molinari,Marcela Garabalino,Elisa Heber,Marcelo Miller,Maria Itoiz,Romina…

2011

“Sequential” boron neutron capture therapy (BNCT): A novel approach to BNCT for the treatment of oral cancer in the hamster cheek pouch model

Authors:   Ana Molinari,Emiliano Pozzi,Andrea Hughes,Elisa Heber,Marcela Garabalino,Silvia Thorp,Marcelo Miller,Maria Itoiz,Romina Aromando,David Nigg,Jorge…

10B concentration evaluation in autoradiography images by optical density measurements

Authors:   A. Portu,G. Saint Martin,D. Brandizzi,O.A. Bernaola,R.L. Cabrini, Journal: Applied Radiation and…

2010

Early effect of boron neutron capture therapy mediated by boronophenylalanine (BPA-BNCT) on mast cells in premalignant tissue and tumors of the hamster cheek pouch

Authors:   Romina Aromando,Verónica Trivillin,Elisa Heber,Emiliano Pozzi,Amanda Schwint,María Itoiz, Journal: Oral Oncology https://doi.org/10.1016/j.oraloncology.2010.02.007…

Evaluation of the radiosensitivity of the oxygenated tumor cell fractions in quiescent cell populations within solid tumors

Authors:   Shin Masunaga,Hideko Nagasawa,Yong Liu,Yoshinori Sakurai,Hiroki Tanaka,Genro Kashino,Minoru Suzuki,Yuko Kinashi,Koji Ono Journal:…

Influence of manipulating hypoxia in solid tumors on the radiation dose-rate effect in vivo, with reference to that in the quiescent cell population

Authors:   Shin Masunaga,Ryoichi Hirayama,Akiko Uzawa,Genro Kashino,Takushi Takata,Hiroki Tanaka,Minoru Suzuki,Yuko Kinashi,Yong Liu,Sachiko Koike,Koichi…

2009

Boron biodistribution study in colorectal liver metastases patients in Argentina

Authors:   J. Cardoso,S. Nievas,M. Pereira,A. Schwint,V. Trivillin,E. Pozzi,E. Heber,A. Hughes,P. Sanchez,E. Bumaschny,M.…

Boron neutron capture therapy at the crossroads: Challenges and opportunities

Authors:   Rolf Barth Journal: Applied Radiation and Isotopes https://doi.org/10.1016/j.apradiso.2009.03.102 Abstract: Over the…

Boronophenylalanine uptake in C6 glioma model is dramatically increased by l-DOPA preloading

Authors:   S. Capuani,T. Gili,M. Bozzali,S. Russo,P. Porcari,C. Cametti,M. Muolo,E. D’Amore,B. Maraviglia,G. Lazzarino,F.…

2008

Boron neutron capture therapy for glioblastoma

Authors:   Tetsuya Yamamoto,Kei Nakai,Akira Matsumura Journal: Cancer Letters https://doi.org/10.1016/j.canlet.2008.01.021 Abstract: Boron neutron…

Enhancement of neutron radiation dose by the addition of sulphur-33 atoms

Authors:   I Porras, Journal: Physics in Medicine and Biology https://doi.org/10.1088/0031-9155/53/7/L01 Abstract: The…

L-DOPA Preloading Increases the Uptake of Borophenylalanine in C6 Glioma Rat Model: A New Strategy to Improve BNCT Efficacy

Authors:   Silvia Capuani,Tommaso Gili,Marco Bozzali,Salvatore Russo,Paola Porcari,Cesare Cametti,Emanuela D’Amore,Marco Colasanti,Giorgio Venturini,Bruno Maraviglia,Giuseppe…

Localized amyloidosis and Alzheimer’s disease: The rationale for weekly long-term low dose amyloid-based fractionated radiotherapy

Authors:   Bistolfi F. Journal: Neuroradiology Journal https://doi.org/10.1177/197140090802100513 Abstract: Amyloidosis, a plasma cell…

2007

Effect of Boron Neutron Capture Therapy (BNCT) on normal liver regeneration: Towards a novel therapy for liver metastases

Authors:   Jorge Cardoso,Veronica Trivillin,Elisa Heber,David Nigg,Osvaldo Calzetta,Herman Blaumann,Juan Longhino,Maria Itoiz,Eduardo Bumaschny,Emiliano Pozzi,Amanda…

Molecular targeting and treatment of an epidermal growth factor receptor-positive glioma using boronated cetuximab

Authors:   Gong Wu,Weilian Yang,Rolf Barth,Shinji Kawabata,Michele Swindall,Achintya Bandyopadhyaya,Werner Tjarks,Behrooz Khorsandi,Thomas Blue,Amy Ferketich,Ming…

Synthesis of cetuximab-immunoliposomes via a cholesterol-based membrane anchor for targeting of EGFR

Authors:   Xiaogang Pan,Gong Wu,Weiliang Yang,Rolf Barth,Werner Tjarks,Robert Lee Journal: Bioconjugate Chemistry https://doi.org/10.1021/bc060174r…

2006

Effects of boron neutron capture therapy on human oral squamous cell carcinoma in a nude mouse model

Authors:   Akitoshi Kamida,Shigeki Obayashi,Itsuro Kato,Koji Ono,Minoru Suzuki,Kenji Nagata,Yoshinori Sakurai,Yoshiaki Yura Journal: International…

Homogeneous boron targeting of heterogeneous tumors for boron neutron capture therapy (BNCT): Chemical analyses in the hamster cheek pouch oral cancer model

Authors:   Elisa Heber,Verónica Trivillin,David Nigg,Maria Itoiz,Beatriz Gonzalez,Raúl Rebagliati,Daniel Batistoni,Erica Kreimann,Amanda Schwint, Journal:…

Neutron producing target for accelerator based neutron capture therapy

Authors:   Bayanov B., Belov V., Taskaev S. Journal: Journal of Physics https://doi.org/10.1088/1742-6596/41/1/051…

Pharmacokinetic study of BSH and BPA in simultaneous use for BNCT

Authors:   Kunio Yokoyama,Shin Miyatake,Yoshinaga Kajimoto,Shinji Kawabata,Atsushi Doi,Toshiko Yoshida,Tomoyuki Asano,Mitsunori Kirihata,Koji Ono,Toshihiko Kuroiwa…

2005

Boron neutron capture therapy for glioblastoma multiforme

Authors:   Catharina Rij,Abraham Wilhelm,Wolfgang Sauerwein,Arie Loenen, Journal: Pharmacy World and Science https://doi.org/10.1007/s11096-004-2850-7…

2004

Combination of boron neutron capture therapy and external beam radiotherapy for brain tumors

Authors:   Rolf Barth,John Grecula,Weilan Yang,Joan Rotaru,Marta Nawrocky,Nilendu Gupta,Brent Albertson,Amy Ferketich,Melvin Moeschberger,Jeffrey Coderre,Einar…

2003

Biodistribution of a carborane-containing porphyrin as a targeting agent for Boron Neutron Capture Therapy of oral cancer in the hamster cheek pouch

Authors:   Erica Kreimann,Michiko Miura,María Itoiz,Elisa Heber,Ricardo Garavaglia,Daniel Batistoni,Raúl Rebagliati,María Roberti,Peggy Micca,Jeffrey Coderre,Amanda…

Experimental application of boron neutron capture therapy to undifferentiated thyroid carcinoma

Authors:   Maria Dagrosa,Mabel Viaggi,Juan Longhino,Osvaldo Calzetta,Romulo Cabrini,Martín Edreira,Guillermo Juvenal,Mario Pisarev Journal: International…

2001

Accelerators for cancer therapy

Authors:   Lennox A.J. Journal: Radiation Physics and Chemistry https://doi.org/10.1016/S0969-806X(01)00244-4 Abstract: The vast…

In vivo imaging of the neutron capture therapy agent BSH in mice using 10B MRI

Authors:   Peter Bendel,Natalia Koudinova,Yoram Salomon Journal: Magnetic Resonance in Medicine https://doi.org/10.1002/mrm.1154 Abstract:…

2000

In vivo evaluation of carborane gadolinium-DTPA complex as an MR imaging boron carrier

Authors:   Hiroyuki Nakamura,Hiroshi Fukuda,Frank Girald,Tooru Kobayashi,Jun’ichi Hiratsuka,Takashi Akaizawa,Hisao Nemoto,Jianping Cai,Katsuya Yoshida,Yoshinori Yamamoto…

On the optimal energy of epithermal neutron beams for BNCT

Authors:   Bisceglie E., Colangelo P., Colonna N., Santorelli P., Variale V. Journal:…

The effects of boron neutron capture therapy on liver tumors and normal hepatocytes in mice

Authors:   Minoru Suzuki,Shin Masunaga,Yuko Kinashi,Masao Takagaki,Yoshinori Sakurai,Toru Kobayashi,Koji Ono Journal: Japanese Journal…

1990-1999

A Comparative Review of the Pharrnacokinetics of Boric Acid in Rodents and Humans

Authors:   J.F. Murray, Journal: Biological Trace Element Research https://doi.org/10.1007/bf02783146 Abstract: The pharmacokinetics…

A History of Boron Neutron Capture Therapy of Brain Tumours

Authors:   Daniel N. Slatkin, Journal: Brain https://doi.org/10.1093/brain/114.4.1609 Abstract: Boron neutron capture therapy…

A review: CNS effects and normal tissue tolerance in dogs

Authors:   Patrick Gavin,Susan Kraft,Rene Huiskamp,Jeffrey Coderre Journal: https://doi.org/10.1023/a:1005773331737 Abstract: Large animal studies…

Boron neutron capture enhanced fast neutron radiotherapy for malignant gliomas and other tumors

Authors:   Thomas Buchholz,George Laramore,Keith Stelzer,Rudolf Risler,Peter Wootton,Thomas Griffin Journal: Journal of Neuro-Oncology…

1980-1989

Boron-loaded macromolecules in experimental physiology: tracing by neutron capture radiography

Authors:   Borje Larssont,Detlef Gabels,Hans Borner Journal: https://doi.org/10.1088/0031-9155/29/4/006 Abstract: Please note that terms…

Complex Formation of p-Boronophenylalanine With Some Monosaccharides

Authors:   Yoshihiro Mori, Akio Suzuki, Kazuo Yoshino, Hidetake Kakihana Journal: Pigment Cell…

1970-1979

Neuropathologic study of fourteen cases of malignant brain tumour treated by boron-10 slow neutron capture radiation

Authors:   AK Asbury,RG Ojeman,SL Nielsen,W. Sweet, Journal: Neuropathol Exp Neurol https://doi.org/10.1097/00005072-197204000-00005 Abstract:

The effect of increasing exposures of the 10-B(n,alpha)7-Li reaction on the skin of man

Authors:   J. Archambeau, Journal: Radiology https://doi.org/10.1148/10.1148/94.1.179 Abstract:

1960-1969

Boron-Slow Neutron Capture Therapy of Gliomas

Authors:   W. Sweet,A. Soloway,G. Brownell, Journal: Acta Radiologica: Therapy, Physics, Biology https://doi.org/10.3109/02841866309135070…

Chemistry of Boranes. VIII.l Salts and Acids of B10,H10-2 and B12H12-2

Authors:   E.L. Muetterties,J.H. Balthis,Y.T. Chia,W.H. Knoth,H.C. Miller, Journal: Inorganic Chemistry https://doi.org/10.1021/ic50013a030 Abstract:

Effect of Thermal Neutrons on Central Nervous System. Apparent Tolerance of Central Nervous System Structures in Man

Authors:   L. Farr,W. Calvo,W. Haymaker,S. Lippincot,Y.L. Yamamoto,E.E. Stickley, Journal: Archives of Neurology…

Evaluation of boron compounds for use in neutron capture therapy of brain tumors. I. Animal investigations.

Authors:   William Sweet,Albert Soloway,R. Wright, Journal: Journal of Pharmacology and Experimental Therapeutics…

Evaluation of boron compounds for use in neutron capture therapy of brain tumors. II. Studies in man.

Authors:   William Sweet,Albert Soloway,R. Wright, Journal: Journal of Pharmacology and Experimental Therapeutics…

Evaluation of two boron-containing drugs for use in the proposed neutron-capture irradiation of gliomas

Authors:   Albert Soloway,D.S. Gordon, Journal: Journal of Neutropathology and Experimental Neurology https://doi.org/10.1097/00005072-196007000-00008…

1950-1959

Correlation of Drug Penetration of Brain and Chemical Structure

Authors:   A.H. Soloway, Journal: Science https://doi.org/10.1126/science.128.3338.1572-a Abstract:

Pathological study of eight patients with glioblastoma multiforme treated by neutron capture therapy using boron 10

Authors:   John Godwin,Lee Farr,William Sweet,James Robertson, Journal: Cancer https://doi.org/10.1002/1097-0142(1955)8:3%3C601::aid-cncr2820080326%3E3.0.co;2-r Abstract:

The possible use of neutron-capturing isotopes such as boron 10 in the treatment of neoplasms. I. Intracranial tumors

Authors:   W. Sweet,M. Javid, Journal: Journal of Neutrosurgery https://doi.org/10.3171/jns.1952.9.2.0200 Abstract:

1940-1949

Physical and Biological Considerations in the Use of Slow Neutrons for Cancer Therapy

Authors:   Paul Zahl,Franklin Cooper, Journal: Radiology https://doi.org/10.1148/37.6.673 Abstract: