Accelerator-based BNCT projects

Several accelerator-based BNCT facilities have been constructed in recent years, and many are still under construction and planning. At the table below you can find all accelerator-based BNCT projects worldwide relevant for the beginning of 2024.

#	Name of the project	Location	Accelerator type	Purpose	Current status
1	C-BENS	Particle Radiation Oncology Research Center of Kyoto University in Kumatori, Japan	Cyclotron	BNCT research	experimental use
2	NeuCure (BNCT30)	Southern Tohoku BNCT Research Center, Fukushima, Japan	Cyclotron	Clinical BNCT	patient treatment
3	NeuCure (BNCT30)	Kansai BNCT Medical Center, Osaka Medical College, Osaka, Japan	Cyclotron	Clinical BNCT	patient treatment
4	NCC CICS-1	National Cancer Center Hospital, Tokyo, Japan	RFQ	Clinical BNCT	phase I clinical trial
5	CICS-2	Edogawa Hospital, Japan	RFQ	Clinical BNCT	clinical trial
6	iBNCT	Ibaraki Neutron Medical Reserch Center, University of Tsukuba, Japan	RFQ+DTL	Clinical BNCT	experimental use
7	nuBeam	Helsinki University Hospital, Finland	Electrostatic	Clinical BNCT	commissioning
8	nuBeam	Shonan Kamakura General Hospital in Kanagawa Prefecture, Japan	Electrostatic	Clinical BNCT	commissioning
9	NeMeSis	Granada University Hospital, Spain	Electrostatic	Clinical BNCT	under development
10	NeuPex	Xiamen Humanity Hospital, Xiamen City, China	Electrostatic Tandem	Clinical BNCT	clinical trial
11	Alphabeam	Fondazione Centro Nazionale Adroterapia Oncologica (CNAO), Pavia, Italy	Electrostatic Tandem	Clinical BNCT	under construction
12	VITA	Budker Institute of Nuclear Physics, Novosibirsk, Russia	Electrostatic Tandem	BNCT research	experimental use
13	VITA	Blokhin National Medical Research Center of Oncology, Moscow, Russia	Electrostatic Tandem	Clinical BNCT	under construction
14	NUANS (Dynamitron)	Nagoya University, Japan	Electrostatic	BNCT research	experimental use
15	SARAF-LiLiT	Soreq Nuclear Research Center, Israel	RFQ+HWR	Multi-purpose research	experimental use
16	ESQ	CNEA, Buenos Aires, Argentina	ESQ	BNCT research	under construction
17	D-BNCT01	Dongguan Neutron Science Center, Dongguan campus of IHEP, China	RFQ	BNCT research	experimental use
18	D-BNCT02	Dongguan People’s Hospital, China	RFQ	Clinical BNCT	under construction
19	A-BNCT	Gachon University Gil Medical Center, Songdo, Incheon, South Korea	RFQ+DTL	Clinical BNCT	preclinical trial
20	KIRAMS AB-BNCT	Korea Institute of Radiological and Medical Sciences (KIRAMS), Seoul, South Korea	Electrostatic	BNCT research	under construction
21	HF ADNF	Birmingham University, UK	Electrostatic	Multi-purpose research	commissioning
22	Legnaro-RFQ	Legnaro National Laboratory, Italian Institute of Nuclear Physics (INFN), Legnaro (Padova), Italy	RFQ	BNCT research	under development
23	E_LibANS	University of Torino, Italy	Electron LINAC	Multi-purpose research	experimental use
24	CYCIAE-14B (CIAE AB-BNCT)	China Institute of Atomic Energy (CIAE), Beijing, China Tai’an Central Hospital, Tai’an, China	Cyclotron	BNCT research	commissioning
25	LU AB-BNCT	Fujian Medical University Union Hospital (Mazu Hospital), Putian City, Fujian Province, China	RFQ	Clinical BNCT	commissioning
26	Heron AB-BNCT	China Medical University Hsinchu Hospital, Zhubei City, Hsinchu County, Taiwan	Cyclotron	Clinical BNCT	commissioning
27	X-TANS	Xi’an Jiaotong University, Xi’an, China	RFQ	Multi-purpose research	under development
28	NeuCure (BNCT30)	Boao BNCT Center, Boao, China	Cyclotron	Clinical BNCT	under construction

References:

1. International Atomic Energy Agency. Nuclear Technology Review 2020
2. International Atomic Energy Agency. Advances in Boron Neutron Capture Therapy
3. Y. Kiyanagi et al. Status of accelerator-based BNCT projects worldwide
4. K. Ono. Prospects for the new era of boron neutron capture therapy and subjects for the future
5. M. Dymova et al. Boron neutron capture therapy: current status and future perspectives
6. R.F. Barth et al. Boron neutron capture therapy of cancer: where do we stand now?