2011 Article Boron imaging ICNCT14 Physics

10B concentration evaluation in autoradiography images by optical density measurements

Applied Radiation and Isotopes, 2011

Authors:   A. Portu,G. Saint Martin,D. Brandizzi,O.A. Bernaola,R.L. Cabrini,
Journal: Applied Radiation and Isotopes
Abstract: The quantification and analysis of the tracks forming the autoradiography image of a tissue section is essential for the measurement of particle emitter concentration and distribution (e.g. 10B) in the sample. Conventional counting techniques cannot be used when track density is high because of track overlapping. A densitometry supported by image analysis method suitable for these cases has been developed. Optical density measurements obtained for boron solutions of known concentrations showed a linear behavior in the range of concentrations under consideration.