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2021 Article Dosimetry Physics

Study of the upper energy limit of useful epithermal neutrons for Boron Neutron Capture Therapy in different tissues

Radiation Physics and Chemistry, 2021

Authors:   Torres-Sánchez P., Porras I., Arias de Saavedra F., Praena J.
Journal: Radiation Physics and Chemistry
https://doi.org/10.1016/j.radphyschem.2021.109490
Abstract: In Boron Neutron Capture Therapy (BNCT), the IAEA recommendations limit the epithermal range to 10 keV. Few works have shown the possibility to increase this limit. In particular, in a previous work we showed this possibility by means of simulations of the dose on a simple phantom of a 4-component ICRU tissue. This possible increment is very relevant for the future accelerator-based neutron sources for BNCT. The present work is based on more realistic MCNP6.2 simulations at neck, brain and abdomen. Several parameters and Figures of Merit have been evaluated for different beam apertures and beam divergences. The results show that neutrons above 10 keV can be useful for BNCT. The exact limit of the epithermal range depends on the location of the tumor.