Teachings of our translational studies on boron neutron capture therapy (BNCT): thinking “outside the box”

Authors:   Amanda Schwint,Marcela Garabalino,Andrea Hughes,Emiliano Pozzi,Elisa Heber,Mónica Palmieri,Verónica Trivillin,
Journal: Therapeutic Radiology and Oncology
https://doi.org/10.21037/tro.2019.05.03
Abstract: BNCT is a technique for the treatment of solid tumors. BNCT is considered a binary technique because it involves two components that exert little or no action individually but induce a significant effect when they combine. BNCT is based on the combination of neutron irradiation and the administration of 10 B compounds that are incorporated selectively by tumor tissue via different mechanisms, depending on the boron carrier.