Reprint of Localized dose delivering by ion beam irradiation for experimental trial of establishing brain necrosis model

Authors:   Takushi Takata,Natsuko Kondo,Yoshinori Sakurai,Hiroki Tanaka,Takashi Hasegawa,Kyo Kume,Minoru Suzuki,
Journal: Applied Radiation and Isotopes
https://doi.org/10.1016/j.apradiso.2015.10.008
Abstract: Localized dose delivery techniques to establish a brain radiation necrosis model are described. An irradiation field was designed by using accelerated protons or helium ions with a spread-out Bragg peak. Measurement of the designed field confirmed that a high dose can be confined to a local volume of an animal brain. The irradiation techniques described here are very useful for establishing a necrosis model without existence of extraneous complications.