2015 Article ICNCT16 In-vivo Studies Others Physics Radiobiology

Reprint of Localized dose delivering by ion beam irradiation for experimental trial of establishing brain necrosis model

Applied Radiation and Isotopes, 2015

Authors:   Takushi Takata,Natsuko Kondo,Yoshinori Sakurai,Hiroki Tanaka,Takashi Hasegawa,Kyo Kume,Minoru Suzuki,
Journal: Applied Radiation and Isotopes
Abstract: Localized dose delivery techniques to establish a brain radiation necrosis model are described. An irradiation field was designed by using accelerated protons or helium ions with a spread-out Bragg peak. Measurement of the designed field confirmed that a high dose can be confined to a local volume of an animal brain. The irradiation techniques described here are very useful for establishing a necrosis model without existence of extraneous complications.