Nine-year interval recurrence after treatment of boron neutron capture therapy in a patient with glioblastoma: A case report

Authors:   Toshiyuki Okazaki,Teruyoshi Kageji,Yoshifumi Mizobuchi,Takeshi Miyamoto,Shinji Nagahiro,
Journal: Applied Radiation and Isotopes
https://doi.org/10.1016/j.apradiso.2013.12.029
Abstract: Boron neutron capture therapy (BNCT) has been reported to be effective in the patients with glioblastoma multiforme (GBM). Median survival time (MST) of GBM patients treated with BNCT is approximately two years. GBM patients surviving 2 or 3 years are considered long-term survivors. In general, most recurrences are local and dissemination is rare. We report an unusual patient with three recurrences; the first and the second recurrences were local, and the third recurrence was dissemination nine years after BNCT.