2011 Article ICNCT14 Treatment plannings

Epithermal neutron beam interference with cardiac pacemakers

Applied Radiation and Isotopes, 2011

Authors:   H. Koivunoro,T. Serén,H. Hyvönen,P. Kotiluoto,P. Iivonen,I. Auterinen,T. Seppälä,L. Kankaanranta,S. Pakarinen,M. Tenhunen,S. Savolainen,
Journal: Applied Radiation and Isotopes
Abstract: In this paper, a phantom study was performed to evaluate the effect of an epithermal neutron beam irradiation on the cardiac pacemaker function. Severe malfunction occurred in the pacemakers after substantially lower dose from epithermal neutron irradiation than reported in the fast neutron or photon beams at the same dose rate level. In addition the pacemakers got activated, resulting in nuclides with half-lives from 25min to 115d. We suggest that BNCT should be administrated only after removal of the pacemaker from the vicinity of the tumor.