2020 Article Boron Compounds Chemistry ICNCT18 Special Issue(ARI)

Comparison of 18FBPA uptake with 18FDG uptake in cancer patients

Applied Radiation and Isotopes, 2020

Authors:   Igaki H., Nakamura S., Kurihara H., Abe Y., Nishioka S., Fujii R., Nakamura M., Nakayama Y., Morita T., Okamoto H., Imahori Y., Itami J.
Journal: Applied Radiation and Isotopes
Abstract: For the patients who underwent 18fluorinated para-boronophenylalanine (18FBPA) positron emission tomography (PET) and 18fluorodeoxyglucose (18FDG) PET within a period of 2 weeks, maximum standardized uptake value (SUVmax), tumor-to-normal tissue ratio (TNR), and tumor-to-blood ratio (TBR) for 18FBPA were compared with SUVmax for 18FDG. A total of 30 patients were selected for comparison. SUVmax for 18FBPA was correlated the best with SUVmax for 18FDG. Subsequently, the SUVmax correlation between 18FBPA and 18FDG were verified among 82 patients. The correlation factor was 0.4825.

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